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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Clin Immunol. 2012 Oct 7;145(3):209–223. doi: 10.1016/j.clim.2012.09.012

Figure 6.

Figure 6

Defective Treg suppressive function in MG patients is associated with elevated levels pro-inflammatory cytokines and failure to up-regulate the production of IL-10. The cytokines IL-6 (A), IL-17 (B), INF-γ (C), IL-10 (D) and TGF-β (E) were measured in the supernatants of the proliferation assays from anti-CD3 stimulated cultures after 4 days of proliferation. Respective cytokine levels are plotted for Tresp (CD4+CD25−) cultures (1:0) and Tresp/Treg co-cultures (1:1) for MG patients (n = 15) and healthy controls (n = 14). Significant differences are indicated.