Table 3.
Hemodynamic responses to expiratory loading at rest and during moderate exercise
|
|
||||||
|---|---|---|---|---|---|---|
| Healthy | Heart failure | |||||
| S | 5 | 10 | S | 5 | 10 | |
| Rest | ||||||
| MAP (mmHg) | 100 ± 11 † | 100 ± 12 | 100 ± 12 | 78 ± 11 | 79 ± 13 | 79 ± 13 |
| SVR (dyn·s/cm5) | 1409 ± 342 † | 1414 ± 364 | 1422 ± 369 | 930 ± 350 | 932 ± 353 | 956 ± 346 |
| SV (ml) | 67 ± 10 † | 65 ± 11 | 61 ± 10 | 70 ± 9 | 72 ± 11 | 69 ± 11 |
| CO (L/min) | 4.4 ± 0.6 | 4.4 ± 0.9 | 4.2 ± 0.9 | 4.5 ± 0.9 | 4.6 ± 0.9 | 4.5 ± 0.9 |
| Exercise | ||||||
| MAP (mmHg) | 115 ± 13 * † ‡ | 107 ± 12 | 109 ± 15 | 90 ± 9 * | 91 ± 11 | 92 ± 10 |
| SVR (dyn·s/cm5) | 818 ± 149 * ‡ | 719 ± 146 | 720 ± 170 | 674 ± 323 * | 683 ± 336 | 693 ± 344 |
| SV (ml) | 87 ± 17 † | 73 ± 13 | 77 ± 12 | 92 ± 14 | 96 ± 11 | 95 ± 10 |
| CO (L/min) | 9.3 ± 1.8 | 8.9 ± 2.1 | 9.0 ± 1.9 | 7.7 ± 1.5 | 8.4 ± 1.2 | 8.4 ± 1.4 |
S: spontaneous breathing, 5: expiratory load of 5 cmH2O, 10: expiratory load of 10 cmH2O, MAP: mean arterial pressure, SVR: systemic vascular resistance, SV: stroke volume, CO: cardiac output.
*
main effect for expiratory loading,
†
main effect for group
‡
group and condition interaction.