. Author manuscript; available in PMC: 2013 Dec 1.

Published in final edited form as: Med Sci Sports Exerc. 2012 Dec;44(12):2315–2321. doi: 10.1249/MSS.0b013e318266ebc3

Table 1. Subject demographics.

	AA Genotype	AT/TT Genotype
n	10	8
Age (years)	24±8	21±7
Height (cm)	168±10	169±5
Weight (kg)	70±17	56±8^*
BMI (kg/m²)	25±4	20±2^*
FVC (L)	3.87±1.37	3.36±1.10
FVC (%predicted)	65±37	29±29^*
FEV₁ (L/sec)	2.92±1.33	2.55±.99
FEV₁ (%predicted)	60±39	25±25^*
FEV₁/FVC (%)	71±15	72±8
FEF₅₀ (%predicted)	50±35	27±14
MVV (L/min)	112±48	96±28
MVV (%)	72±19	102±67

Values are mean±SD; BMI=Body mass index; FVC=forced vital capacity; FEV₁= Forced expiratory volume in 1 second; FEF₅₀=Forced expiratory flow at 50% of forced vital capacity; MVV= Maximum voluntary ventilation; AA genotype= homozygous for SCNN1A resulting in alanine at amino acid 663; AT/TT genotype= at least one copy of SCNN1A resulting in threonine at amino acid 663;

p<0.05 between groups.