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. Author manuscript; available in PMC: 2012 Nov 20.
Published in final edited form as: Immunity. 2012 Mar 8;36(3):491–501. doi: 10.1016/j.immuni.2012.01.014

Figure 1.

Figure 1

Effect of SAHA on the frequency of latently infected cells. PBMCs from patients on HAART were isolated and cultured in basal medium with or without 500 nM SAHA for six days. Efavirenz, raltegravir and enfuvirtide were added in the culture to prevent further rounds of viral replication. Resting CD4+ T cells were then isolated from the cultures. The frequency of cells harboring replication-competent HIV-1 was then measured using a previously described co-culture assay (Siliciano and Siliciano. 2005).