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Atg7KO mice demonstrate spontaneous recurrent seizures and increased mortality a, Percentage of wild-type (circle) and Atg7KO (square) mice that displayed behavioral seizure activities by 20 weeks of age. b, Percentage of survival of wild-type and Atg7KO mice by 20 weeks of age. c, d, Representative electrographic recording in a WT mouse during a typical wake period (c) and an Atg7KO mouse during a spontaneous seizure episode (d).
