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. Author manuscript; available in PMC: 2012 Nov 20.
Published in final edited form as: Drug Discov Today Dis Models. 2011 May 6;7(3-4):123–130. doi: 10.1016/j.ddmod.2011.04.001

Figure 2.

Figure 2

Bradykinin (BK) causes vasodilation in an endothelium-intact mouse pulmonary artery. A fluorescence image of a pulmonary artery segment used for the contraction experiments (A). Pulmonary arterial smooth muscle was stained in red with smooth muscle α-actin, while pulmonary artery endothelium was stained in green with lectin. Representative tension record showing 40K-induced active tension before and during the application of 20 μM BK (B). Summarized data (mean ± SE) showing absolute tension before (basal) and after application of 40K in the absence and presence (BK) of BK (left; n = 4), and 40K-induced active tension with or without BK treatment (right; n = 4) (C). **P < 0.01 vs. basal or 40K-BK.