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. 2012 Nov 1;2012:357368. doi: 10.1155/2012/357368

Table 1.

Effect of palmatine and other drugs employed on transfer latency (TL) of mice using elevated plus maze.

Treatments Dose (kg)−1 TL (sec) on 10th day TL (sec) on 11th day
Control (vehicle) for 10 days 10 mL 20.25 ± 2.27 17.13 ± 1.24
Physostigmine for 10 days 0.1 mg 16.38 ± 1.39 8.25 ± 0.88b
Scopolamine 0.4 mg 19.25 ± 2.16 28.25 ± 1.85b
Diazepam 1 mg 19.14 ± 2.11 24.57 ± 2.30a
Palmatine for 10 days 0.1 mg 18.37 ± 1.73 14.13 ± 1.73
Palmatine for 10 days 0.5 mg 15.87 ± 1.72 9.88 ± 0.83a
Palmatine for 10 days 1 mg 15.75 ± 2.30 8.75 ± 0.75b
Palmatine for 10 days + scopolamine on 10th day 1 mg + 0.4 mg 15.14 ± 1.98 15.57 ± 1.2c
Palmatine for 10 days + diazepam on 10th day 1 mg + 1 mg 20.75 ± 2.20 17 ± 1.50d

n = 8 in each group. Values are expressed as Mean ± SEM. Data was analyzed by one-way ANOVA followed by Tukey's post-hoc test.

F(8, 60) = 1.417; P = 0.02079 (10th day);

F(8, 60) = 21.034; P < 0.0001 (11th day);

a P < 0.05 as compared to control;

b P < 0.01 as compared to control;

c P < 0.001 as compared to scopolamine treated group;

d P < 0.01 as compared to diazepam treated group.