Table 1.
Treatments | Dose (kg)−1 | TL (sec) on 10th day | TL (sec) on 11th day |
---|---|---|---|
Control (vehicle) for 10 days | 10 mL | 20.25 ± 2.27 | 17.13 ± 1.24 |
Physostigmine for 10 days | 0.1 mg | 16.38 ± 1.39 | 8.25 ± 0.88b |
Scopolamine | 0.4 mg | 19.25 ± 2.16 | 28.25 ± 1.85b |
Diazepam | 1 mg | 19.14 ± 2.11 | 24.57 ± 2.30a |
Palmatine for 10 days | 0.1 mg | 18.37 ± 1.73 | 14.13 ± 1.73 |
Palmatine for 10 days | 0.5 mg | 15.87 ± 1.72 | 9.88 ± 0.83a |
Palmatine for 10 days | 1 mg | 15.75 ± 2.30 | 8.75 ± 0.75b |
Palmatine for 10 days + scopolamine on 10th day | 1 mg + 0.4 mg | 15.14 ± 1.98 | 15.57 ± 1.2c |
Palmatine for 10 days + diazepam on 10th day | 1 mg + 1 mg | 20.75 ± 2.20 | 17 ± 1.50d |
n = 8 in each group. Values are expressed as Mean ± SEM. Data was analyzed by one-way ANOVA followed by Tukey's post-hoc test.
F(8, 60) = 1.417; P = 0.02079 (10th day);
F(8, 60) = 21.034; P < 0.0001 (11th day);
a P < 0.05 as compared to control;
b P < 0.01 as compared to control;
c P < 0.001 as compared to scopolamine treated group;
d P < 0.01 as compared to diazepam treated group.