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Aggregation-prone regions detected by AGGRESCAN within the 20 amino acids flanking the Nter and Cter sides of the first (A) and second (B) regions containing conserved catalytic residues in kinase domains. Aggregation-prone stretches are shown in red in the alignment of representative proteins corresponding to different classes (AGC, CAMK, CMGC, Other, STE, TK, and TKL) in human (Hs), fruit fly (Dm), and yeast (Sc). The conserved catalytic residues are highlighted in gray.
