Table 2.
Proportion of puberal state, values >95th of the entire group, and number of abnormalities according to antecedents of diabetes or metabolic syndrome in their parents compared with healthy parents.
| Variable in offspring |
Healthy father and mother n = 114 (1) |
Diabetic father and healthy mother n = 4 (2) |
Diabetic mother and healthy father n = 78 (3) |
Both parents with diabetes n = 22 (4) |
Diabetic father and MS, healthy mother n = 19 (5) |
Diabetic mother and MS, healthy father n = 23 (6) |
P |
|---|---|---|---|---|---|---|---|
| Pubertal stage n (%) | |||||||
| Prepuber | 18 (15.8) | 11 (24.4) | 13 (16.6) | 5 (22.7) | 5 (26.3) | 3 (13.0) | 0.41 |
| Puber | 27 (23.6) | 10 (22.2) | 23 (29.5) | 0 (0) | 4 (21.1) | 4 (17.4) | |
| Postpuber | 41 (35.9) | 14 (31.1) | 22 (28.2) | 9 (40.9) | 8 (42.1) | 11 (47.8) | |
| Young adult | 98 (87.9) | 10 (22.2) | 20 (25.6) | 8 (36.4) | 2 (10.5) | 5 (21.7) | |
| Variables >95th n (%) | 114 | 45 | 78 | 22 | 19 | 23 | |
| BMI | 48 (42.1) | 31 (68.9) | 34 (43.6) | 11 (50.0) | 11 (57.9) | 9 (39.1) | 0.04 |
| SBP | 46 (40.3) | 22 (48.9) | 34 (43.6) | 12 (54.5) | 8 (42.1) | 12 (52.2) | 0.84 |
| DBP | 46 (40.3) | 21 (46.6) | 33 (42.3) | 11 (50.0) | 8 (42.1) | 12 (52.2) | 0.81 |
| Glucose | 34 (29.8) | 22 (48.9) | 34 (43.6) | 10 (45.4) | 9 (47.4) | 12 (52.2) | 0.11 |
| Total cholesterol | 41 (35.9) | 23 (51.1) | 38 (48.7) | 11 (50.0) | 14 (73.7) | 12 (52.2) | 0.03 |
| HDL-Chol | 32 (28.1) | 12 (26.7) | 29 (37.2) | 7 (31.8) | 8 (42.1) | 12 (52.2) | 0.20 |
| Triglycerides | 48 (42.1) | 21 (46.6) | 38 (48.7) | 14 (63.6) | 12 (63.1) | 12 (52.2) | 0.33 |
| Number of variables <95th | 2 (2-3) | 4 (3-4) | 3 (2-3) | 3.5 (2–5) | 4 (2–4) | 3 (2–5) | 0.009 |