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. 2012 Nov 15;61(12):3322–3332. doi: 10.2337/db11-1653

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© 2012 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 1. — Comparison of DNA methylation in skeletal muscle of men with (FH⁺) vs. men without (FH⁻) a family history of T2D. The top KEGG pathways of genes, which exhibit decreased (A) and increased (B) methylation in skeletal muscle of FH⁺ (n = 15) vs. FH⁻ (n = 13) men, respectively, with the expected number of genes (white), the observed number of genes (black), and the total number of genes in the pathway in parentheses. The P values were adjusted for multiple testing.