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A: Semiquantitative assessment of relative changes in graft volumes revealed the protective effect of MN-siB2M probe (n = 6; P < 0.05 starting 2 weeks after adoptive transfer compared with control group). B: Kaplan-Meier curve shows animals transplanted with control (red) and MN-siB2M-treated (black) islets. Development of diabetes was defined as the occurrence of hyperglycemia (blood glucose level >250 mg/dL on two consecutive measurements, n = 6; P = 0.0006).
