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. 2012 Nov 15;61(12):3148–3155. doi: 10.2337/db12-0029

FIG. 2.

FIG. 2.

Muscle lipid levels in chow-fed and HFD-fed WT and SphK1 Tg mice. A: Ceramide levels (chow WT n = 7; chow SphK1 Tg n = 5; HFD WT n = 15; HFD SphK1 Tg n = 15). B: Fold change in total ceramide content (data expressed relative to chow group of the same genotype; n = 15). C: S1P content in muscle of HFD-fed WT (n = 8) and SphK1 Tg mice (n = 7). D: Muscle sphingosine content (WT n = 8; SphK1 Tg n = 7). E: Muscle sphingomyelin levels (chow WT n = 5; chow SphK1 Tg n = 5; HFD WT n = 7; HFD SphK1 Tg n = 7). F: Muscle DAG profile (chow WT n = 5; chow SphK1 Tg n = 5; HFD WT n = 7; HFD SphK1 Tg n = 7). G: Muscle TAG content (chow WT n = 6; chow SphK1 Tg n = 7; HFD WT n = 10; HFD SphK1 Tg n = 8). H: PE levels (chow WT n = 5; chow SphK1 Tg n = 5; HFD WT n = 7; HFD SphK1 Tg n = 7). I: PC levels (chow WT n = 5; chow SphK1 Tg n = 5; HFD WT n = 7; HFD SphK1 Tg n = 7). Data are mean ± SEM. *P < 0.05 vs. wild type. †Main effect for genotype, P < 0.05. ‡Main effect for diet, P < 0.05.