Table 3.

Linkage disequilibrium analysis of KIR genes in CEPH

	Wn
	2DL2	2DL3	2DL5B	2DP1	2DL1	3DL1	3DS1	2DL5A	2DS3	2DS5	2DS1	2DS4
2DS2	0.976	−0.988	0.512	−0.687	−0.687	−0.181	0.193	0.130	0.373	0.151	0.164	−0.164
	<0.001	<0.001	<0.001	<0.001	<0.001	0.025	0.014	NS	<0.001	NS	0.038	0.038
2DL2		−0.964	0.526	−0.705	−0.705	−0.139	0.150	0.086	0.386	0.098	0.122	−0.122
		<0.001	<0.001	<0.001	<0.001	NS	NS	NS	<0.001	NS	NS	NS
2DL3			−0.506	0.707	0.707	0.202	−0.186	−0.124	−0.366	−0.145	−0.186	0.186
			<0.001	<0.001	<0.001	0.009	0.016	NS	<0.001	NS	0.016	0.016
2DL5B				0.136	0.136	−0.316	0.325	0.223	0.838	0.172	0.286	−0.286
				NS	NS	<0.001	<0.001	0.007	<0.001	0.037	<0.001	<0.001
2DP1					1.000	−0.064	0.090	0.110	0.172	0.050	0.090	−0.090
					<0.001	NS	NS	NS	0.029	NS	NS	NS
2DL1						−0.064	0.090	0.110	0.172	0.050	0.090	−0.090
						NS	NS	NS	0.029	NS	NS	NS
3DL1							−0.952	−0.887	−0.382	−0.806	−0.984	0.984
							<0.001	<0.001	<0.001	<0.001	<0.001	<0.001
3DS1								0.902	0.427	0.783	0.936	−0.936
								<0.001	<0.001	<0.001	<0.001	<0.001
2DL5A									0.411	0.810	0.902	−0.902
									<0.001	<0.001	<0.001	<0.001
2DS3										0.118	0.356	−0.356
										NS	<0.001	<0.001
2DS5											0.819	−0.819
											<0.001	<0.001
2DS1												−1.000
												<0.001

LD values with p<0.001 in bold. 2DL4, 3DL2, 3DL3, and 3DP1 have been omitted from the table, as all three have a frequency of 100%

NS not significant