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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2011 Nov 17;18(3):396–405. doi: 10.1016/j.bbmt.2011.11.013

Figure 5. CDDO-me administration increases the number of hematopoietic progenitor cells in the bone marrow and spleen.

Figure 5

Mouse bone marrow and spleens were collected after the previously described treatment schedule and stained for lineage markers, c-kit, Sca-1 and 7-AAD to exclude dead cells. 7-AAD emits in the same fluorescent channel as the lineage markers used in this study (PE-Cy-5); thus dead cells were eliminated from gating during lineage exclusion. A, Representative flow plots of spleens and bone marrow HPCs are displayed. B and C, total bone marrow and spleen hematopoietic progenitor cells were determined. Statistical differences were determined by one-way ANOVA with Tukey’s post-test and a p-value<0.05 was considered significant.