Table 1.
Anthropometric measures, glucose metabolism parameters, and serum adiponectin and C-reactive protein at baseline.
| Parameter (unit) | Caffeinated coffee (n = 17) | Decaffeinated coffee (n = 15) | No coffee (n = 13) | P value* |
|---|---|---|---|---|
| Body weight (kg) | 77 (70–84) | 75 (71–80) | 79 (78–83) | 0.22 |
| Waist circumference (cm) | 93 (89–99) | 91 (88–95) | 95 (90–97) | 0.46 |
| Plasma glucose (mmol/L) | ||||
| Fasting | 6.0 (5.3–6.2) | 6.1 (5.3–7.4) | 5.8 (5.4–6.3) | 0.68 |
| 2-hour | 8.5 (7.3–9.9) | 10.1 (7.7–12.8) | 9.2 (7.4–12.9) | 0.35 |
| AUC† | 18.3 (15.9–20.1) | 20.6 (17.5–23.7) | 20.8 (18.5–23.2) | 0.16 |
| Plasma insulin (pmol/L) | ||||
| Fasting | 57 (38–66) | 34 (27–71) | 58 (52–66) | 0.53 |
| 2-hour | 551 (347–868) | 314 (187–565) | 472 (312–854) | 0.24 |
| AUC† | 999 (676–1289) | 570 (376–978) | 881 (629–1057) | 0.13 |
| Composite ISI | 3.6 (2.3–4.6) | 4.8 (2.4–7.9) | 3.4 (2.1–5.0) | 0.38 |
| HOMA-IR | 2.0 (1.3–2.5) | 1.2 (0.9–3.3) | 2.0 (1.8–2.9) | 0.51 |
| Total adiponectin (μg/mL) | 4.9 (4.1–8.2) | 5.8 (5.6–6.3) | 4.8 (3.9–6.5) | 0.66 |
| HMW adiponectin (μg/mL) | 2.6 (1.5–4.9) | 3.1 (2.2–4.4) | 2.2 (1.7–3.6) | 0.73 |
| C-reactive protein (mg/L) | 0.49 (0.26–0.85) | 0.23 (0.19–0.83) | 0.42 (0.29–0.72) | 0.24 |
AUC: area under the curve; HMW: high-molecular weight; HOMA-IR: homeostasis model assessment of insulin resistance; ISI: insulin sensitivity index.
Values are medians and interquartile ranges (25th and 75th percentiles) in parentheses.
*Overall difference based on Kruskal-Wallis test.
†Hour was used for the time scale in the oral glucose tolerance test.