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. Author manuscript; available in PMC: 2013 Nov 15.
Published in final edited form as: Cancer Res. 2012 Nov 15;72(22):5956–5965. doi: 10.1158/0008-5472.CAN-12-2127

Figure 4. Safety evaluation and localization of the ELP depot in mice.

Figure 4

Mean body weight following i.t. administration of unlabeled ELP or [131I]ELP120-Tyr7 in nude mice bearing (A) FaDu xenografts and (B) PC-3 xenografts, Data represent the mean and SEM, n = 7–12. (C) The biodistribution of radioactivity in mice bearing FaDu tumor xenografts treated with an ELP depot. Data represent the mean and SEM, n = 5–6. (D) H&E stained photomicrograph of the tumor injection site 48 hrs after i.t. administration of [131I]ELP120-Tyr7 at 50 × magnification, and (E) autoradiography of the corresponding tumor injection site of (D)