Table 2.
Consistently reported up-regulated miRNAs (n = 26) in profiling studies (lung cancer tissue versus normal)
|
miRNA namea |
No. of studies with same direction (reference) |
No. of tissue samples tested |
Subset of studies with fold change |
|||
|---|---|---|---|---|---|---|
| No. of studies | No. of tissue samples tested | Mean fold change | Range | |||
| miR-210 |
9 (19,22,24,25,26,27,29,30,32) |
796 |
6 |
449 |
2.65 |
1.51 - 5.10 |
| miR-21 |
7 (19,21,25,28,29,30,32) |
448 |
6 |
240 |
4.39 |
1.74 - 13.60 |
| miR-182 |
6 (22,24,26,27,28,32) |
496 |
4 |
357 |
6.34 |
1.85 - 19.00 |
| miR-31 |
6 (21,22,26,27,29,32) |
425 |
5 |
357 |
2.89 |
1.58 - 4.80 |
| miR-205 |
5 (26,27,28,29,30) |
417 |
3 |
141 |
23.20 |
2.99 - 54.30 |
| miR-200b |
5 (19,25,26,28,32) |
262 |
4 |
194 |
3.69 |
1.30 - 9.80 |
| miR-183 |
4 (22,24,27,28) |
388 |
3 |
317 |
5.94 |
2.11 - 11.60 |
| miR-203 |
3 (24,26,30) |
347 |
0 |
- |
- |
- |
| miR-196a |
3 (22,27,28) |
317 |
3 |
317 |
37.50 |
2.10 - 101.80 |
| miR-708 |
3 (22,27,29) |
301 |
3 |
301 |
3.20 |
1.85 - 5.50 |
| miR-92b |
3 (27,28,32) |
151 |
3 |
151 |
3.71 |
1.54 - 6.80 |
| miR-193b |
3 (21,26,27) |
149 |
2 |
81 |
4.68 |
2.56 - 6.80 |
| miR-106a |
2 (24,30) |
279 |
0 |
- |
- |
- |
| miR-21* |
2 (22,27) |
271 |
2 |
271 |
2.23 |
2.16 - 2.30 |
| miR-135b |
2 (21,22) |
222 |
2 |
222 |
2.29 |
2.28 - 2.31 |
| miR-96 |
2 (22,23) |
218 |
2 |
218 |
171.56 |
2.30 - 340.81 |
| miR-17-5p |
2 (24,27) |
136 |
1 |
65 |
3.80 |
- |
| miR-20b |
2 (24,28) |
117 |
1 |
46 |
5.70 |
- |
| miR-18a |
2 (26,28) |
114 |
1 |
46 |
7.80 |
- |
| miR-200a |
2 (24,32) |
111 |
1 |
40 |
1.86 |
- |
| miR-93 |
2 (24,32) |
111 |
1 |
40 |
1.68 |
- |
| miR-130b |
2 (26,32) |
108 |
1 |
40 |
1.57 |
- |
| miR-200c |
2 (24,29) |
101 |
1 |
30 |
1.66 |
- |
| miR-375 |
2 (28,32) |
86 |
2 |
86 |
5.35 |
2.89 - 7.80 |
| miR-20a |
2 (20,24) |
83 |
0 |
- |
- |
- |
| miR-18b | 2 (20,26) | 80 | 0 | - | - | - |
a The asterisk is part of the miRNA nomenclature system and is not linked to any footnote specific to this table.