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. 2012 Jun 6;31(1):54. doi: 10.1186/1756-9966-31-54

Table 3.

Consistently reported down-regulated miRNAs (n = 28) in profiling studies (lung cancer tissue versus normal)

miRNA namea
 No. of studies with same direction (reference)
 Total number of tissue samples tested
 Subset of studies with fold change
      No. of studies Total number of tissue samples tested Mean fold change Range
miR-126
 10 (19,21,25,26,27, 28,29,30,31,32)
 587
 8
 311
 0.33
 0.00 - 0.69
miR-30a
 8 (19,21,25,26,27,28,29,31)
 339
 7
 271
 0.36
 0.04 - 0.61
miR-451
 6 (19,21,25,27,28,29)
 265
 6
 265
 0.37
 0.01 - 0.53
miR-486-5p
 5 (19,22,26,27,28)
 437
 4
 369
 0.39
 0.13 - 0.53
miR-30d
 5 (21,25,28,29,31)
 154
 5
 154
 0.34
 0.08 - 0.57
miR-145
 4 (26,28,30,32)
 362
 2
 86
 0.23
 0.09 - 0.38
miR-143
 4 (21,28,30,32)
 310
 3
 102
 0.33
 0.13 - 0.59
miR-139-5p
 3 (22,27,29)
 301
 3
 301
 0.55
 0.40 - 0.64
miR-126*
 3 (21,25,30)
 280
 2
 72
 0.33
 0.20 - 0.45
miR-140-3p
 3 (26,27,28)
 179
 2
 111
 0.29
 0.17 - 0.42
miR-138
 3 (25,26,32)
 164
 2
 96
 0.64
 0.56 - 0.72
miR-30b
 3 (25,28,29)
 132
 3
 132
 0.41
 0.11 - 0.58
miR-486
 3 (25,29,32)
 126
 3
 126
 0.44
 0.34 - 0.53
miR-101
 3 (21,27,31)
 87
 3
 87
 0.34
 0.24 - 0.48
miR-125a
 2 (24,30)
 279
 0
 -
 -
 -
miR-198
 2 (27,30)
 273
 1
 65
 0.25
 -
miR-144*
 2 (22,27)
 271
 2
 271
 0.31
 0.14 - 0.48
miR-140
 2 (30,32)
 248
 1
 40
 0.66
 -
miR-218
 2 (22,32)
 246
 2
 246
 0.61
 0.60 - 0.62
miR-32
 2 (20,30)
 220
 0
 -
 -
 -
miR-338-3p
 2 (26,27)
 133
 1
 65
 0.20
 -
miR-99a
 2 (27,28)
 111
 2
 111
 0.31
 0.20 - 0.42
miR-195
 2 (26,29)
 98
 1
 30
 0.53
 -
miR-497
 2 (26,29)
 98
 1
 30
 0.66
 -
miR-30c
 2 (25,29)
 86
 2
 86
 0.58
 0.54 - 0.61
miR-130a
 2 (21,27)
 81
 2
 81
 0.46
 0.45 - 0.46
miR-16
 2 (28,29)
 76
 2
 76
 0.37
 0.18 - 0.57
miR-139 2 (29,32) 70 2 70 0.53 0.49 - 0.58

a The asterisk is part of the miRNA nomenclature system and is not linked to any footnote specific to this table.