Table 2.

The clinical score of the mice was performed according to the table below

Score	Observation
0	No discernible clinical signs
1	Hunched back, slightly ruffled fur
2	Very ruffled fur, reduced rate of movement, developing motor impairments
3	Very ruffled fur, impaired balance/coordination, hypothermic, severe motor impairments such as ataxia, hemiplegia and paraplegia, convulsions, fitting
4	Very little movement, convulsions, fitting
5	Loss of consciousness/coma