Skip to main content
. 2012 Nov 20;7(11):e49940. doi: 10.1371/journal.pone.0049940

Figure 9. CD4+ cells regulate inflammatory lymphangiogenesis.

Figure 9

A. LYVE-1+ vessel density in popliteal lymph nodes 7 days after CFA/OVA induced lymph node lymphangiogenesis in control, CD4+ cell depleted, or CD4 knockout (CD4KO) mice. Representative cross sectional histology of the lymph node (blue DAPI stain, red LYVE-1 stain) are shown to the right. B., C. Expression of VEGF-A (A) and VEGF-C (B) protein by ELISA in popliteal lymph nodes harvested 7 days after CFA/OVA induced lymph node lymphangiogenesis in control or CD4 depleted mice.