Table 1.
HtrA1 mRNA expression in esophageal cancer tissue and its relationship with clinicopathological factors
| Pathologic parameter | Cases | HtrA1-positive rate (%) | χ2 | P |
|---|---|---|---|---|
| Normal tissue |
63 |
43 (68.25) |
8.2286 |
0.004* |
| Carcinoma tissue |
63 |
27 (42.86) |
||
| Sex |
||||
| Male |
50 |
23 (46.00) |
0.9773 |
0.323 |
| Female |
13 |
4 (30.77) |
||
| Age |
||||
| < 60 |
19 |
6 (31.58) |
1.4130 |
0.235 |
| ≥ 60 |
44 |
21 (47.73) |
|
|
| Size of primary carcinoma (cm) |
||||
| < 3 |
36 |
15 (41.67) |
0.0486 |
0.825 |
| ≥ 3 |
27 |
12 (44.44) |
||
| Degree of differentiation |
||||
| Well and moderately differentiated |
34 |
19 (55.88) |
5.1169 |
0.024* |
| Poorly differentiated |
29 |
8 (27.59) |
||
| Pathological stage |
|
|
|
|
| I − II |
33 |
19 (57.58) |
6.1303 |
0.013* |
| III − IV |
30 |
8 (26.67) |
|
|
| Lymph nodes metastasis |
|
|
|
|
| Negative |
26 |
17 (65.38) |
9.1739 |
0.002* |
| Positive |
37 |
10 (27.03) |
|
|
| Distant metastasis |
|
|
|
|
| Negative |
31 |
21 (67.74) |
15.4325 |
0.000* |
| Positive | 32 | 6 (18.75) |