Table 1. Sources and targets of α-syn intrabodies.
Intrabody | Type | Target | Reference | Source |
---|---|---|---|---|
D5E |
Human scFv |
Oligomeric α-syn |
Emadi et al. 2007 |
Tomlinson I and J antibody libraries |
10H |
Human scFv |
Oligomeric α-syn |
Emadi et al. 2009 |
Tomlinson I and J antibody libraries |
D10 |
Human scFv |
Pan-specific |
Zhou et al., 2004 |
Human scFv phage Griffin I library |
VH14 (NAC14) | Human Nanobody | Hydrophobic non-amyloid component (NAC) of α-synuclein, amino acids 53–95 | Lynch et al. 2008 | Human non-immune yeast surface display library |