Table 2. Dose-dependent tumor growth delay with U87 tumors treated with CE-355621.

Sample	Time to reach 1000 mm3 (days)
Vehicle	6.2 ± 0.2
25 μg CE-355621	9.9 ± 0.2***
100 μg CE-355621	16.1 ± 1.1***
200 μg CE-355621	22.3 ± 0.4***

^*** p < 0.001(by Student’s t-test). Increasing doses of CE-355621 induce progressively longer tumor growth delay in U87MG tumors. The size of each tumor in Figure 7A was measureon c-Met in GTL-16 xenograft tumorsd every 2–3 d and the time to reach 1000 mm³ (days) from the start of treatment was determined. Values are means ± SEM.