Table 2.
Survival analysis according to univariate Cox proportional hazard models
|
Characteristics |
LRFS |
MFS |
OS |
||||||
|---|---|---|---|---|---|---|---|---|---|
| CHR | 95% CI | P | CHR | 95% CI | P | CHR | 95% CI | P | |
|
Age |
|
|
|
|
|
|
|
|
|
| < 45 vs. ≥ 45 |
1.66 |
1 to 2.98 |
0.05 |
1.27 |
0.91 to 1.78 |
0.157 |
1.02 |
1.02 to 1.03 |
0.01 |
|
Size |
|
|
|
|
|
|
|
|
|
| < 5 cm vs. ≥ 5 cm |
2.70 |
1.97 to 3.81 |
<0.001 |
2.47 |
1.12 to 5.51 |
0.026 |
1.74 |
1.16 to 2.63 |
0.025 |
|
Depth |
|
|
|
|
|
|
|
|
|
| Superficial vs. Deep |
1.24 |
0.78 to 1.95 |
0.363 |
1.46 |
0.82 to 2.6 |
0.198 |
1.32 |
0.92 to 1.88 |
0.130 |
|
Grade |
|
|
|
|
|
|
|
|
|
| Low vs. High |
2.1 |
1.4 to 3.4 |
<0.001 |
3.45 |
1.63 to 7.373 |
<0.001 |
1.28 |
1.01 to 1.63 |
0.04 |
|
Margin |
|
|
|
|
|
|
|
|
|
| < 10 mm vs. ≥ 10 mm | 6.344 | 3.01 to 13.37 | <0.001 | 3.98 | 2.2 to 7.11 | <0.001 | 4.6 | 2.6 to 8.4 | <0.001 |
CHR, Cox Hazard Ratio; CI, confidence interval; LRFS, local recurrence-free survival; MFS, metastasis-free survival; OS, overall survival.