Table 2.

Crude and Adjusted Attributable Fraction and Attributable Number of Cases in First 2 Years of the Global Enteric Multicenter Study: India, Ages 12–23 Months (364 Cases, 374 Controls)

Pathogen	Cases With Pathogen	Unadjusted Analysis				Adjusted Analysis
		ORa	P Valueb	AF	Attributable Cases	ORa	P Valueb	AF	Attributable Cases
Rotavirus	104	22.5	<.0001	0.273	99	36.4	<.0001	0.278	101
Shigella	30	11.4	.0003	0.075	27	38.9	<.0001	0.080	29
ETEC LT/ST or ST	34	2.6	.004	0.057	21	4.3	.0006	0.072	26
Cryptosporidium	45	1.7	.031	0.052	19	2.4	.006	0.073	26
Vibrio cholerae O1	19	8.8	.002	0.046	17	9.1	.002	0.046	17
Adenovirus 40/41	18	6.0	.003	0.041	15	9.5	.002	0.044	16
Entamoeba histolytica	7	3.0	.15	0.013	5	10.3	.038	0.017	6

Abbreviations: AF, attributable fraction; ETEC, enterotoxigenic Escherichia coli; LT, heat-labile enterotoxin; OR, odds ratio; ST, heat-stable enterotoxin.

^a OR: ratio of the odds of moderate-to-severe diarrhea when the putative pathogen is present to the odds when it is absent. OR >1 indicates a positive association.

^b P value from logistic regression.