Table 1.

Two-by-Two Tables Showing Distributions of Exposure (E) and Outcome (O) or Disease Defining Case Status (D) as a Basis for the Conceptual Framework of the Reconstructed Population Method

			O
			+	−	Total	Risk	RR	95% CI
A	Source Population
	E	+	70	4930	5000	0.014	2.6
		−	508	94 492	95 000	0.005
B	CoCa
	E	+	25	475	500	0.050	2.2
		−	43	1857	1900	0.023
C	NC
	E	+	45	4455	4500	0.010	2.0
		−	465	92 635	93 100	0.005
D	CoCo
	E	+	1	110	111	0.009	1.9
		−	11	2278	2289	0.005
			D
			+	−	(Odds)	(OR)
E	CC study
	E	+	500	111	4.505	5.4
		−	1900	2289	0.83
			O
			+	−
F	CoCa
	E	+	25	475	500	0.050	2.2	1.4–3.6
		−	43	1857	1900	0.023
G	CoCo
	E	+	1	110	111	0.009	1.9	.24–14.4
		−	11	2278	2289	0.005
H	CoCa + CoCo
	E	+	26	585	611	0.043	3.3	2.1–5.2
		−	54	4135	4189	0.013

Abbreviations: CC, case/control; CI, confidence interval; CoCa, cohort of cases; CoCo, cohort of controls; D, case-defining illness; NC, noncases; OR, odds ratio; RR, relative risk.