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. 2012 Nov 20;7(11):e50201. doi: 10.1371/journal.pone.0050201

Figure 6. Virulence recovery of H. capsulatum amy1-null yeasts complemented with the P. brasiliensis AMY1 gene.

Figure 6

Macrophage survival is measured as the remaining macrophage DNA after incubation of macrophages with Histoplasma yeasts. Macrophage DNA remaining at 8 days post infection was normalized to uninfected populations of macrophages. Data represent three independent assays. Error bars represent the standard deviation. (*)Unpaired t-tests between amy1-Δ+pCR41 and amy1-Δ+pEC87 or pEC90; P-value <0.0001.