Figure 1.

Reverse transcriptase and protease mutations among participants with virologic failure. A, All observed major reverse transcriptase and 151 complex mutations are presented, plus nonmajor mutations emergent in 5 or more participants with virologic failure in either group. V35I, K101E, I135T, and T200A are nonmajor. B, All observed major protease (L33F-L90M) and atazanavir/ritonavir (ATV/r) minor mutations (L10F-I93L) are presented, plus additional mutations emergent in 5 or more participants with virologic failure in either group (I72V and V77I). The one participant with G73T at failure had G73A at pretreatment. Amino acid mixtures were separated into individual mutations; mutations are ordered by codon within major, minor, and additional mutations. Abbreviation: EFV, efavirenz.