Table 5.
Concordantly regulated SAGE transcripts from the ROP-Os/+ mouse model (as compared to C57-Os) and transcripts derived from microarray of human kidney biopsies from patients with FSGS (as compared to normal controls)
| TAG count in ROP-Os | TAG count in C57-Os | Genes concordantly regulated between mouse model and human Glomerulus | log Fold Change | q-value | Genes concordantly regulated between mouse model and human tubuloninterstitium | log Fold Change | q- value |
|---|---|---|---|---|---|---|---|
| 0 |
7 |
Slc 22a6 |
−0.42 |
0.00 |
Slc22a6 |
−0.22 |
0.00 |
| 0 |
9 |
Slc4a4 |
−0.32 |
0.00 |
|
|
|
| 1.35 |
13 |
Aqp1 |
−0.30 |
0.00 |
|
|
|
| 5.4 |
0 |
Psmb5 |
0.21 |
0.00 |
|
|
|
| 5.4 |
0 |
Pcbp1 |
0.24 |
0.00 |
|
|
|
| 5.4 |
0 |
Psma3 |
0.31 |
0.00 |
|
|
|
| 6.75 |
20 |
Pdzk1ip1 |
−0.15 |
0.02 |
|
|
|
| 74.25 |
45 |
Igfbp7 |
0.14 |
0.02 |
|
|
|
| 12.15 |
3 |
Mdh2 |
0.16 |
0.02 |
|
|
|
| 9.45 |
0 |
Vamp8 |
0.11 |
0.03 |
|
|
|
| 8.1 |
1 |
Tmbim4 |
0.12 |
0.03 |
|
|
|
| 5.4 |
0 |
Ndufb11 |
0.21 |
0.03 |
|
|
|
| 4.05 |
16 |
Lifr |
−0.09 |
0.05 |
Lifr |
−0.27 |
0.00 |
| 12.15 |
3 |
Sod1 |
0.06 |
0.09 |
|
|
|
| 16.2 |
6 |
Herpud1 |
−0.07 |
0.14 |
|
|
|
| 2.7 |
13 |
Atp6v1a |
−0.03 |
0.15 |
|
|
|
| 8.1 |
42 |
Nrp2b |
−0.03 |
0.15 |
|
|
|
| 2.7 | 12 | 0.11 | 0.11 | Id2 | −0.40 | 0.00 |