Figure 4.

Effect of hypothermic treatments on the Et-1 induced infarct volume. There was no infarct volume in the S and the S + H group (n = 7 and 4 respectively, data not shown). (A) Delaying hypothermia up to 60 minutes after the administration of Et-1 still induced enough neuroprotection to reduce the infarct volume significantly. The amount of animals in each hypothermic group was 7. *Significantly different compared to the infarct volume of the N group (n = 12). ^§Significantly different from each other (p < 0.05). (B) shows the infarct volume for the different treatment protocols.