Table 2.
Organ distribution (1 h post-injection) of [68Ga]6 and [68Ga]7 in BALB/c nu/nu mice
| Organ | Monomer [68Ga]6 | Dimer [68Ga]7 |
|---|---|---|
| Blood |
0.53 ± 0.04 |
0.31 ± 0.03 |
| Heart |
0.83 ± 0.08 |
0.90 ± 0.12 |
| Lung |
2.36 ± 0.27 |
2.25 ± 0.24 |
| Spleen |
17.90 ± 2.87 |
17.88 ± 4.53 |
| Liver |
1.43 ± 0.19 |
1.29 ± 0.11 |
| Kidney |
139.44 ± 21.40 |
133.43 ± 18.88 |
| Muscle |
1.00 ± 0.24 |
0.90 ± 0.01 |
| Intestine |
1.14 ± 0.46 |
0.57 ± 0.14 |
| Brain |
0.40 ± 0.19 |
0.17 ± 0.01 |
| PC-3 tumor |
1.30 ± 0.12 |
0.93 ± 0.53 |
| LNCaP tumor (n = 5) | 4.89 ± 1.34 | 8.22 ± 1.78 |
Injection dose was 1 to 2 MBq/mouse, 0.1 to 0.2 nmol. Data are expressed as % ID/g ± SD, n = 3.