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Differences in the immunogenicity of various MSP142proteins after homologous and heterologous immunizations of outbred ICR mice were tested by ELISA for reactivity against homologous (Panel A) and heterologous (Panel B) MSP142proteins. X-axis = time point (two weeks post first or second immunization) using ELISA plate antigens: MSP142 3D7, FVO and CAMP. Data are expressed as the mean μg/mL mouse IgG (+/−SEM). n = 20 mice/group, two independent immunization experiments.
