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Concomitant JAK2 mutation and SFRP-2 hypermethylation in MPN patients
| CML (n = 10) | PV (n = 10) | ET (n = 10) | MF (n = 27) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SFRP-2 |
U |
M |
U |
M |
U |
M |
U |
M |
|
| JAK2, wt |
10 |
0 |
1 |
1 |
4 |
1 |
12 |
1 |
|
| JAK2V617F | 0 | 0 | 6 | 2 | 2 | 3 | 8 | 6 | |
CML, chronic myeloid leukemia; ET, essential thrombocythemia; M, methylated; MF, myelofibrosis; PV, polycythemiavera; U, unmethylated; wt = negative for JAK2V617F.
