Table 2.
Multivariable analysis revealed that the pre-operative CRP-level is an independent prognostic marker for cancer- specific survival
| Variable | P value | HR (95%CI) |
|---|---|---|
| Age [years] 1 |
<0.001 |
1.03 (1.01-1.04) |
| Sex |
0.74 |
|
| female |
|
1 |
| male |
|
0.96 (0.72-1.26) |
| T stage |
0.07 |
|
| pT1a |
|
1 |
| pT1b |
0.74 |
1.08 (0.69-1.69) |
| pT2 |
0.34 |
1.30 (0.76-2.22) |
| pT3a |
0.006 |
1.90 (1.20-2.99) |
| pT3b |
0.20 |
1.35 (0.86-2.13) |
| pT3c |
0.35 |
2.00 (0.46-8.59) |
| pT4 |
0.89 |
0.94 (0.42-2.20) |
| LN metastases 2 |
<0.001 |
|
| N- |
|
1 |
| N+ |
|
3.59 (2.46-5.25) |
| Pulmonary or visceral metastases 2 |
<0.001 |
|
| M- |
|
1 |
| M+ |
|
3.23 (2.31-4.50) |
| Differentiation |
0.02 |
|
| G1 |
|
1 |
| G2 |
0.01 |
1.97 (1.16-3.34) |
| G3 |
0.003 |
2.47 (1.36-4.51) |
| G4 |
0.01 |
4.13 (1.38-12.34) |
| Histological subtype |
0.17 |
|
| non ccRCC |
|
1 |
| ccRCC |
|
1.43 (0.85-2.41) |
| CRP-value 2 |
<0.001 |
|
| <4 mg/l |
|
1 |
| 4-10 mg/l |
0.03 |
1.66 (1.06-2.59) |
| >10 mg/l | <0.001 | 2.58 (1.83-3.64) |
1continuous metric variable, 2 at the time of surgery.