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EC50 at 0 mV (mean ± S.E.M.) for GlyH-101 for wt and mutant CFTRs, with and without modification with iodoacetamide
| CFTR | EC50 at 0 mV |
|---|---|
| μM | |
| wt | 1.1 ± 0.11 (n = 4) |
| K95C | 1.4 ± 0.35 (n = 4) |
| F337C | 1.8 ± 0.06 (n = 3) |
| F337C + iodoacetamide | 2.4 ± 0.29 (n = 3) |
| T338C | 3.7 ± 0.27 (n = 3) |
| T338C + iodoacetamide | 24 ± 2.6 (n = 3) |
