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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: J Orthop Res. 2012 Aug 15;31(2):183–190. doi: 10.1002/jor.22207

Figure 1.

Figure 1

Knee joint histopathology. 16-week-old Prg4 mutant (Prg4−/−) and wildtype (Prg4+/+) mice were administered intermittent PTH (1–34) (50μg/kg) or vehicle (VEH) (0.9% NaCl) control subcutaneous injection daily for 6 weeks. Knee joints were isolated from 22-week-old Prg4 mice for histological evaluation. Representative images of H&E stained sagittal knee sections (4X), with (inset) 20X image of the articular cartilage and posterior meniscus (black arrows indicate the acellular layer lining joint surfaces; yellow arrows indicate the secondary deposit associated with PTH-treatment).