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(a,b) Representative measurements of Fura2-AM fluorescence ratio (dashed line, left axis) and contraction (solid line, right axis) in vena cava exposed to low Na+ PSS in the presence of vehicle (a) or 10 μM KB-R7943 (b). (c,d) Summary bar graphs indicating the maximum change in fluorescence ratio (c) and contraction (d) from these same experiments. Black bars represent vehicle-exposed tissues. White bars represent tissues exposed to 10 μM KB-R7943. N=5–6; * = p<0.05 versus vehicle.
