Table 1.
Characteristics of studies analyzing KIRs or KIR ligands.
| Reference | n | Stem cell source | T-cell depletion | Donor type | HLA match | Diagnose |
|---|---|---|---|---|---|---|
| Ruggeri et al. 2002 [3] | 92 | PB | All | Related | Haploidentical | Various |
| Bishara et al. 2004 [6] | 62 | PB | Not all | Related | Haploidentical | Various |
| Symons et al. 2010 [7] | 86 | BM | None | Related | Haploidentical | Various |
| Weisdorf et al. 2012 [8] | 24 | PB | All | Related | Haploidentical | Myeloid |
| Cook et al. 2004 [9] | 220 | ? | ? | Related | HLA match | Lymphoid, myeloid |
| Hsu et al. 2005 [10] | 178 | BM | All | Sibling | HLA match | Various |
| Dalva et al. 2006 [11] | 84 | PB/BM | None | Sibling | HLA match | Various |
| McQueen et al. 2007 [5] | 202 | PB (89%)/BM | None | Sibling | HLA match | Various |
| Kim et al. 2007 [12] | 53 | BM/PB | None | Sibling | HLA match | Myeloid |
| Giebel et al. 2009 [13] | 100 | PB/BM | All | Sibling/unrelated | HLA match (81%) | Various |
| Stringaris et al. 2010 [14] | 246 | PB/BM | All | Sibling | HLA match | Myeloid |
| Davies et al. 2002 [15] | 175 | BM | 34% | Unrelated | HLA mismatch | Various |
| Giebel et al. 2003 [16] | 130 | BM (96%) | 81% | Unrelated | HLA match (47%) | Various |
| Bornhäuser et al. 2004 [17] | 118 | BM/PB | All | Unrelated | HLA match (46%) | Myeloid |
| Schaffer et al. 2004 [18] | 190 | BM/PB | All | Unrelated | HLA match (49%) | Various |
| Beelen et al. 2005 [19] | 374 | BM/PB | None | Unrelated (60%) | HLA match (63%) | CML (63 %) |
| De Santis et al. 2005 [20] |
104 | BM/PB | 14% (BM) | Unrelated | HLA mismatch | Various |
| Kröger et al. 2005 [21] | 73 | PB (63%)/BM | All | Unrelated | HLA match (86%) | Myeloma |
| Farag et al. 2006 [22] | 1571 | BM | None | Unrelated | HLA match (64%) | Various |
| Miller et al. 2007 [23] | 1770 | PB/BM | None | Unrelated | HLA match | Various |
| Yabe et al. 2008 [24] | 1489 | BM | All | Unrelated | HLA match | Various |
| Cooley 2009 [25] | 448 | ? | None | Unrelated | HLA match (47%) | Myeloid |
| Cooley et al. 2010 [26] | 1086 | ? | None | Unrelated | HLA match (50%) | Myeloid, lymphoid |
| Gagne et al. 2009 [4] | 264 | BM | None | Unrelated |
HLA match (62 %) | Various |
| Venstrom et al. 2010 [27] | 1087 | BM (97%) | 19% | Unrelated | HLA match (62%) | Myeloid, lymphoid |
| Brunstein et al. 2009 [28] | 257 | CB | 32% | Unrelated | HLA mismatch (92%) | Various |
| Willemze et al. 2009 [29] | 218 | CB | 81% | Unrelated | HLA mismatch | Various |
BM: bone marrow, PB: peripheral blood, CB: cord blood, and CML: chronic myeloid leukemia.