Table 2.
Expression of genes under the GO term immune response. Values in the three last columns depict fold changes between ApoE knockout and age-matched wild type mice in log2 scale. The majority of genes at 32 and 78 weeks are upregulated.
| Symbol | Description | 6 weeks | 32 weeks | 78 weeks |
|---|---|---|---|---|
| Ccl6 | Chemokine (C-C motif) ligand 6 | −0.17 | 2.25 | 2.23 |
| Cd74 | CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | 0.29 | 1.56 | 1.43 |
| C1qb | Complement component 1, q subcomponent, beta polypeptide | −0.23 | 2.28 | 2.43 |
| H2-Ab1 | Histocompatibility 2, class II antigen A, beta 1 | −0.25 | 1.94 | 2.77 |
| C1qa | Complement component 1, q subcomponent, a polypeptide | −0.08 | 1.98 | 2.18 |
| Tlr2 | Toll-like receptor 2 | 0.14 | 0.99 | 1.38 |
| Ccl7 | Chemokine (C-C motif) ligand 7 | −0.98 | 1.59 | 4.42 |
| C4b | Complement component 4B (Childo blood group) | 0.23 | 1.2 | 1.74 |
| Cblb | Casitas B-lineage lymphoma b | 0.2 | 0.34 | 1.36 |
| Fcgr2b | Fc receptor, IgG, low affinity IIb | −0.1 | 1.93 | 2.19 |
| Cd300lb | CD300 antigen like family member B | −0.46 | 2.83 | 2.87 |
| Susd2 | Sushi domain containing 2 | 0.22 | −0.08 | −1.07 |
| Ccl8 | Chemokine (C-C motif) ligand 8 | 0.33 | 2.92 | 3.01 |
| Cd14 | CD14 antigen | −0.14 | 1.52 | 2.44 |
| Fcgr1 | Fc receptor, IgG, high affinity I | −0.05 | 1.82 | 2.03 |
| Cadm1 | Cell adhesion molecule 1 | −0.57 | 1.5 | 2.01 |
| C2 | Complement component 2 (within H-2S) | −0.81 | 1.02 | −0.03 |
| Clec7a | C-type lectin domain family 7, member a | 0.15 | 3.52 | 3.86 |
| Procr | Protein C receptor, endothelial | −0.25 | 0.77 | 1.02 |
| C1qc | Complement component 1, q subcomponent, C chain | −0.22 | 2.22 | 2.25 |
| Ccl19 | Chemokine (C-C motif) ligand 19 | −0.71 | 1.07 | 1.64 |
| Enpp3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3 | 0.24 | −0.00 | −1.28 |
| Cx3cl1 | Chemokine (C-X3-C motif) ligand 1 | 0.18 | 1.71 | 1.87 |
| Ccl9 | Chemokine (C-C motif) ligand 9 | −0.46 | 1.74 | 2.19 |
| H2-Eb1 | Histocompatibility 2, class II antigen E beta | 0.19 | 1.62 | 2.17 |
| H2-Aa | Histocompatibility 2, class II antigen A, alpha | 0.95 | 2.39 | 2.34 |
| Cxcl12 | Chemokine (C-X-C motif) ligand 12 | −0.34 | 1.1 | 1.95 |
| Enpp1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.14 | 0.37 | 1.08 |
| Rnf19b | Ring finger protein 19B | −0.29 | 0.73 | 2.58 |
| Prg4 | Proteoglycan 4 | 0.16 | 3.33 | 3.99 |
| Irf8 | Interferon regulatory factor 8 | 0.28 | 1.9 | 2.61 |
| Cxcl1 | Chemokine (C-X-C motif) ligand 1 | −0.46 | 1.77 | 2.66 |