Table 6.
Number of Vaccine Recipients with Immune Response Measured at Month 6.5 Visit and Hence Used in the Evaluation of an Immunological Correlate of Risk, for Vaccine Regimens with Time-Constant VE of 50%*.
| Sample Size for Analysis Counting Infections Diagnosed Between 6.5 and 24 Months | |||
|---|---|---|---|
| Number of Vaccine Arms | Expected Number Infections Diagnosed 6.5−24 Months with Immunological Data | Number Uninfected Vaccinee Controls (5:1 Ratio) | Total Number of Immunological Measurements |
| 1 | 53 | 265 | 318 |
| 2 | 106 | 530 | 636 |
| 3 | 159 | 795 | 954 |
| Sample Size for Analysis Counting Infections Diagnosed Between 6.5 and 36 Months | |||
|---|---|---|---|
| Number of Vaccine Arms | Expected Number Infections Diagnosed 6.5−36 Months with Immunological Data | Number Uninfected Vaccinee Controls (5:1 Ratio) | Total Number of Immunological Measurements |
| 1 | 87 | 435 | 522 |
| 2 | 174 | 870 | 1044 |
| 3 | 261 | 1305 | 1566 |