Table 3.
Amphotericin B killing assay with S. brasiliensis strain IPEC 26449 cultured on media without or with different melanin synthesis inducersa
| Time (h) | Mean % survival ± SD |
|||||
|---|---|---|---|---|---|---|
| Minimal medium |
Minimal medium with l-DOPA |
Minimal medium with l-tyrosine |
||||
| 0.5 μg/ml AMB | 2.0 μg/ml AMB | 0.5 μg/ml AMB | 2.0 μg/ml AMB | 0.5 μg/ml AMB | 2.0 μg/ml AMB | |
| 2 | 7.0 ± 0.3 | 1.1 ± 0.5 | 12.5 ± 5.6 | 4.9 ± 1.6 | 70.0 ± 36.2 | 25.8 ± 8.0 |
| 6 | 0.55 ± 0.1 | 0 | 1.8 ± 1.3 | 0 | 8.5 ± 4.4 | 0 |
| 24 | 0.14 ± 0.1 | 0 | 2.0 ± 0.4 | 0 | 4.7 ± 3.8 | 0 |
a
Results are the means ± standard deviations of percent survival rates from at least three different observations. AMB, amphotericin B.