TABLE 2.
Worldwide distribution of the M. tuberculosis shared types (SIT) present among the 10 Colombian XDR-TB isolates as determined using the SITVIT2 database
| SIT (clade) octal no. (SITVIT2 database no.) | Spoligotype | Distribution (%) in regions with ≥3% of a given SIT(s)a | Distribution (%) in countries with ≥3% of a given SIT(s)b |
|---|---|---|---|
| SIT62 (H1) 777777774020731 (497) | ■■■■■■■■■■■■■■■■■■■■■■■■■◽◽◽◽◽◽■◽◽◽◽■■■◽■■■ | AMER-S 40.24, EURO-S 13.68, AMER-N 13.68, EURO-W 8.05, AFRI-E 4.02, AFRI-W 3.62 | COL 37.63, USA 13.68, ITA 8.25, ESP 4.22, FXX 3.62, GMB 3.42 |
| 190 (Beijing) 000000000003731 (179) | ◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽◽■■■■■◽■■■ | ASIA-E 35.2, AMER-N 32.96, AMER-S 16.76, ASIA-SE 5.59 | USA 32.96, CHN 24.58, COL 16.2, JPN 6.7, KOR 3.35 |
| 545 (LAM2) 675737607760771 (8) | ■■◽■■■■◽■■■■◽■■■■■■■◽◽◽◽■■■■■■■■◽◽◽◽■■■■■■■ | AMER-S 50.0, EURO-W 25.0, AMER-N 25.0 | COL 50.0, USA 25.0, FXX 25.0 |
| 881 (unknown) 776377770000731 (72) | ■■■■■■■■◽◽■■■■■■■■■■■■■■◽◽◽◽◽◽◽◽◽◽◽◽■■■◽■■■ | AMER-S 76.0, AMER-N 16.0, EURO-S 8.0 | COL 72.0, USA 16.0, VEN 4.0, ITA 4.0, ESP 4.0 |
| 3010 (S) 776377777740731 (9) | ■■■■■■■■◽◽■■■■■■■■■■■■■■■■■■■■■◽◽◽◽◽■■■◽■■■ | AMER-S 77.78, EURO-S 11.11, AMER-N 11.11 | COL 66.67, USA 11.1, PER 11.1, ITA 11.1 |
Worldwide distribution is reported for regions with SITs representing ≥3% of their total number in the SITVIT2 database. The definition of macrogeographical regions and subregions (http://unstats.un.org/unsd/methods/m49/m49regin.htm) is according to the United Nations. Regions: AFRI (Africa), AMER (Americas), ASIA (Asia), EURO (Europe), and OCE (Oceania), subdivided into E (eastern), M (middle), C (central), N (northern), S (southern), SE (southeastern), and W (western). Furthermore, CARIB (the Caribbean) belongs to the Americas, while Oceania is subdivided in 4 subregions, AUST (Australasia), MEL (Melanesia), MIC (Micronesia), and POLY (Polynesia). Note that in our classification scheme, Russia has been assigned a new subregion by itself (northern Asia) instead of including it among the rest of eastern Europe. That assignment reflects its geographical localization as well as due to the similarity of specific TB genotypes circulating in Russia (a majority of Beijing genotypes) to those prevalent in central, eastern, and southeastern Asia.
The 3-letter country codes are according to http://en.wikipedia.org./wiki/ISO_3166–1_alpha-3; countrywide distribution is shown only for SITs representing ≥3% of their total number in the SITVIT2 database.