TABLE 6.
No. of isolates | Amino acid substitution(s)a in the rrs (16S) gene (1,680 bp) | Kanamycin result by: |
|
---|---|---|---|
Ion Torrentb | Bactec MGIT 960 | ||
1 | G878A | Sensitive | Sensitive |
12 | Wild typea | Sensitive | Sensitive |
1 | A514C, A1401G | Resistant | Resistant |
6 | A1401G | Resistant | Resistant |
3 | A514C | Sensitive | Sensitive |
1 | C492T | Sensitive | Sensitive |
1 | C492T, A514C | Sensitive | Sensitive |
1 | A514C | Sensitive | Sensitive |
Compared to the H37Rv reference strain.
Aminoglycoside resistance is known to occur at positions 1401 (A→G), 1402 (C→T), and 1484 (G→T) (indicated in bold).