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. 2012 Dec;50(12):3845–3852. doi: 10.1128/JCM.00626-12

TABLE 4.

Concordance between MALDI-TOF MS and standard identification methods across major organism categoriesa

Match category Result (% concordance [95% confidence interval])
Gram-positive cocci Gram-positive rods Gram-negative cocci Gram-negative rods
Overall
Enteric Nonfermenting Fastidious Overall
Speciesb 123/126 (97.6% [93.2–99.5]) 87/89 (97.8% [92.1–99.7]) 20/20 (100% [83.2–100]) 154/160 (96.3% [92.0–98.6]) 70/72 (97.2% [90.3–99.7]) 52/53 (98.1% [89.9–100]) 292/302 (96.7% [94.0–98.4]) 522/537 (97.2% [95.4–98.4])
Genusc 131/131 (100% [97.2–100]) 93/93 (100% [96.1–100]) 22/22 (100% [84.6–100]) 159/160 (99.4% [96.6–100]) 74/74 (100% [95.1–100]) 53/53 (100% [93.3–100]) 305/306 (99.7% [98.2–100]) 551/552 (99.8% [99.0–100])
No reliable identificationd 1/1 (100% [25–100]) 6/6 (100% [54.1–100]) 1/1 (100% [25–100]) 0/0 2/3 (66.7% [9.4–99.2]) 3/4 (75% [19.4–99.4]) 5/8 (62.5% [24.5–91.5]) 13/16 (81.3% [54.4–96])
Total 132 99 23 160 77 57 314 568
a

The distribution of identifications by match category was not significantly different across the major organism categories (P = 0.247, chi-square test).

b

Number of isolates concordant to species level with standard method identification/total number of isolates scoring ≥1.9.

c

Number of isolates concordant to genus level with standard method identification/total number of isolates scoring ≥1.7. Isolates scoring <1.7 were considered unreliable for identification by MALDI regardless of their concordance with standard method identification.

d

Number of isolates concordant to genus level with standard method identification/total number of isolates scoring <1.7. Isolates scoring <1.7 were considered unreliable for identification by MALDI regardless of their concordance with standard method identification.