TABLE 1.
MICs of echinocandins for Candida albicans strains with reduced caspofungin susceptibilitya
| Strain | MIC (μg/ml) |
||
|---|---|---|---|
| Anidulafungin | Caspofungin | Micafungin | |
| CAI4 (wild type) | 0.016 | 0.06 | 0.008 |
| CAI4RI (heterozygote) | 1 | 4 | 0.5 |
| NR2 (homozygote) | 8 | 8 | 8 |
| NR3 (homozygote) | 0.5 | 4 | 1 |
| NR4 (heterozygote) | 0.5 | 2 | 0.5 |