TABLE 2.
Comparison of hrHPV genotyping by SPF10-DEIA-LiPA25 in physician-obtained and dry Evalyn Brush samples
| Genotype | hrHPV positivitya detected by SPF10-LiPA25 in: |
κ value (95% CI) | P value | |||
|---|---|---|---|---|---|---|
| Dry Brush and physician-obtained samples | Physician-obtained samples only | Dry Brush samples only | Neither of the two systems | |||
| HPV16 | 13 | 1 | 3 | 117 | 0.850 (0.706–0.994) | 0.625 |
| HPV18 | 8 | 2 | 0 | 124 | 0.881 (0.719–1.000) | 0.500 |
| HPV31 | 8 | 3 | 6 | 117 | 0.604 (0.369–0.839) | 0.508 |
| HPV33 | 5 | 1 | 0 | 128 | 0.905 (0.721–1.000) | 1.000 |
| HPV35 | 2 | 1 | 0 | 131 | 0.796 (0.407–1.000) | 1.000 |
| HPV39 | 2 | 4 | 2 | 126 | 0.378 (0–0.770) | 0.687 |
| HPV45 | 2 | 0 | 0 | 132 | 1.000 (1.000–1.000) | 2.000 |
| HPV51 | 7 | 0 | 4 | 123 | 0.763 (0.540–0.985) | 0.125 |
| HPV52 | 5 | 5 | 5 | 119 | 0.460 (0.177–0.743) | 1.000 |
| HPV56 | 4 | 3 | 3 | 124 | 0.548 (0.226–0.870) | 1.000 |
| HPV58 | 1 | 1 | 0 | 132 | 0.663 (0.044–1.000) | 1.000 |
| HPV59 | 4 | 4 | 0 | 126 | 0.653 (0.339–0.967) | 0.125 |
| HPV66 | 9 | 1 | 4 | 120 | 0.763 (0.563–0.962) | 0.375 |
| HPV68/73 | 1 | 2 | 2 | 129 | 0.318 (0–0.812) | 1.000 |
| HPV39/68/73 | 0 | 2 | 0 | 132 | NCb | 0.500 |
| Any type | 71 | 30 | 29 | 1,880 | 0.691 (0.617–0.766) | 1.000 |
a
Values indicate the number of samples.
b
NC, this quantity cannot be calculated.