TABLE 3.
Agreement in hrHPV positivity (14 hrHPV genotypes) in self-sampled dry Evalyn Brush samples compared to physician-obtained samples with GP5+/6+-LQ in relation to the diagnoses
| Diagnosis | n | hrHPV positivitya detected by GP5+/6+ in: |
κ value (95% CI) | P value | |||
|---|---|---|---|---|---|---|---|
| Dry Brush and physician-obtained samples | Physician-obtained samples only | Dry Brush samples only | Neither of the two systems | ||||
| Negativeb | 70 | 13 | 4 | 4 | 49 | 0.689 (0.490–0.889) | 1.273 |
| BMDc | 28 | 12 | 1 | 3 | 12 | 0.716 (0.460–0.971) | 0.625 |
| CIN 1 | 9 | 4 | 2 | 0 | 3 | 0.571 (0.098–1.000) | 0.500 |
| CIN 2 | 13 | 9 | 1 | 1 | 2 | 0.567 (0.032–1.000) | 1.500 |
| CIN 3 | 14 | 10 | 2 | 0 | 2 | 0.588 (0.107–1.000) | 0.500 |
| Total | 134 | 48 | 10 | 8 | 68 | 0.725 (0.607–0.843) | 0.815 |
Values indicate the number of samples.
Two of these results were not obtained at the same time as the sample for HPV analysis was obtained.
Three of these results were not obtained at the same moment as the sample for HPV analysis was obtained; one of these samples was a vagina top smear. BMD, borderline or mild dyskaryosis.