Fig 3.

CD8⁺ T cell immunodominance profiles are similar following vaccination with LCMV inactivated by H₂O₂, formaldehyde, and heat. C57BL/6 mice were vaccinated with 50 μg purified LCMV inactivated with H₂O₂ (A), formaldehyde (B), or heat (56°C) (C), each formulated with 5 μg MPL. Immunodominance profiles were determined 8 days following vaccination by direct ex vivo stimulation of splenocytes with the panel of 20 H-2^b-restricted LCMV peptides. Graphs show the averages ± SDs of 4 mice per group from 2 independent experiments.