Pathogenesis of rMA15 in STAT1/6−/− mice. (A) Weight loss curves of WT and STAT1/6−/− mice infected with rMA15 (n = 5 for each time point). The error bars indicate standard deviations. (B) H&E staining of WT, STAT1−/−, STAT6−/−, and STAT1/6−/− mice either mock infected with PBS or infected with rMA15. (C) Histological scoring of H&E- stained mouse lungs for WT, STAT1−/−, STAT6−/−, and STAT1/6−/− mice at 9 days p.i.