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. 2012 Dec;86(24):13334–13349. doi: 10.1128/JVI.01689-12

TABLE 1.

Histological scoring criteria

Inflammation Criteria for score of:
0 1 2 3
Interstitial <2 inflammatory cells/alveolar septal diam 2–5 inflammatory cells/alveolar septal diam 6–25 inflammatory cells/alveolar septal diam involving <5% of the parenchyma 6–25 inflammatory cells/alveolar septal diam involving >5% of the parenchyma
Peribronchiolar Rare inflammatory cells Mild; 250–1,000 inflammatory cells/mm2 involving <10% of bronchiolar circumference Moderate; >1,000 inflammatory cells/mm2 involving <25% of bronchiolar circumference Severe; >1,000 inflammatory cells/mm2 involving >25% of bronchiolar circumference
Perivascular Rare inflammatory cells Mild; 250–1,000 inflammatory cells/mm2 involving <10% of arteriolar circumference Moderate; >1,000 inflammatory cells/mm2 involving <25% of arteriolar circumference Severe; >1,000 inflammatory cells/mm2 involving >25% of arteriolar circumference